Michele Migliore's lab

NEW: Job Openings

Academic and Scientific activity

We are interested in understanding how the brain works. For this purpose, we use the available experimental data to design, implement and analyze realistic models of neurons, synapses, and networks. The goal is to uncover the mechanisms underlying higher brain functions, to help the development of innovative therapies to treat brain diseases and dysfunctions. The list of scientific publications will give you an idea of how we do that.
We regularly run dissemination and training events to introduce users interested in applying our models to their scientific problem. See the "Events" tab for more information on past events. The next School on Brain Simulations will be in Bilbao June 3-7 2024. Stay tuned for more info.

National and International Collaborations

Logo of the University of Naples Federico II
University of Naples Federico II
Department of Neuroscience
via Pansini 5, 80131 Naples, Italy
Logo of the European Brain Research Institute
European Brain Research Institute
via del Fosso di Fiorano 64, 00143 Rome, Italy
Logo of the University of Palermo
University of Palermo
Department of Mathematics and Computer Science
via Archirafi, Palermo, Italy
Logo of the CNRS
UMR7275, Valbonne, France

External Funding

EBRAINS-Italy logo
The EBRAINS-Italy EBRAINS-Italy is a new digital research infrastructure, stemming out from the EU-funded Human Brain Project and funded by the Italian Recovery fund (PNRR), gathering an extensive range of data and tools for neuroscience-related research.
PRIN logo
The PRIN HIPPOCOMP In HIPPOCOMP we will use experimental and computational methods to make breakthrough advancements in i) the knowledge on human hippocampal circuits; ii) in the generation of human hippocampus model endowed with realistic connectivity. We will apply forefront imaging methods to collect high resolution data, which will be used to develop custom algorithm allowing to generate cell placement and a plausible connectivity, providing a valuable tool to be endowed with customized single neuron models developed by researchers within the scientific community.
FISA logo
The FISA EIDD major objective is to provide the neuroscience community with a unique, high TRL (8-9), workflow for studying and predicting early neuronal changes (“Targets Data Base-TDB), integrating in-silico biophysically detailed computational models, in vitro experiments, and experimental molecular biology methods, to accelerate the starting of the pre-clinical phase by cutting costs and time.